The Functional Medicine Approach to Managing Inflammation & Chronic Pain
Crafted by: Jonathan Chew

Introduction: Inflammation is the Root of Most Diseases
Inflammation is a natural response to injury or infection, but when it becomes chronic, it leads to pain, autoimmune conditions, and long-term health issues.
Did You Know?
Chronic inflammation is linked to over 90% of chronic diseases, including arthritis, heart disease, and Alzheimerβs.
Pain medications (NSAIDs, steroids) only mask symptoms but donβt fix the root cause.
Functional Medicine focuses on reducing inflammation naturally through diet, gut health, and lifestyle changes.
In this guide, weβll explore:
The hidden causes of chronic inflammation & pain
How Functional Medicine helps reduce inflammation naturally
The best foods, supplements, and lifestyle changes for pain relief
What Causes Chronic Inflammation?
Inflammation is triggered when the immune system is constantly activated, leading to pain, fatigue, swelling, and long-term tissue damage.
Top Root Causes of Chronic Inflammation & Pain:
Gut Dysbiosis & Leaky Gut β Intestinal permeability allows toxins to trigger immune responses.
Blood Sugar Imbalances & Insulin Resistance β Leads to systemic inflammation & metabolic dysfunction.
Nutrient Deficiencies (Omega-3s, Magnesium, Vitamin D) β Weakens anti-inflammatory pathways.
Toxin Exposure (Plastics, Heavy Metals, Pesticides) β Triggers immune system overactivity.
Chronic Stress & High Cortisol β Suppresses immune regulation & worsens inflammation.
Poor Sleep & Circadian Rhythm Imbalances β Increases inflammatory markers like CRP.
Example: A person with joint pain & digestive issues might have gut-related inflammation driving their pain.
Functional Medicineβs Anti-Inflammatory Strategy
Instead of just taking painkillers or anti-inflammatory drugs, Functional Medicine fixes the root causes of inflammation for long-term relief.
How Functional Medicine Reduces Inflammation Naturally:
Heals gut health & prevents leaky gut
Balances blood sugar & insulin resistance
Optimizes nutrient intake & anti-inflammatory foods
Removes hidden toxins that trigger inflammation
Supports the nervous system to lower stress-related inflammation
Example: A person with autoimmune arthritis & fatigue may need gut-healing protocols & omega-3 therapy to reduce symptoms.
Best Anti-Inflammatory Foods for Pain Relief
A whole-food, nutrient-dense diet is the foundation for reducing inflammation naturally.
Top Functional Medicine Foods for Inflammation Reduction:
Wild-Caught Sardine & Omega-3s β Reduces joint pain & stiffness.
Cruciferous Vegetables (Broccoli, Kale, Cauliflower, Brussels Sprouts) β Supports detox & lowers inflammation.
Turmeric & Ginger β Contains curcumin & gingerol, powerful anti-inflammatory compounds.
Dark Berries (Blueberries, Blackberries, Goji berries) β High in polyphenols & antioxidants.
Leafy Greens (Spinach, Swiss Chard, Arugula, Dandelion Greens) β High in magnesium & phytonutrients.
Extra Virgin Olive Oil & Avocados β Rich in monounsaturated fats that lower inflammation.
Foods to Avoid for Chronic Pain & Inflammation:
Refined Sugar & Processed Carbs β Spikes insulin & increases inflammation.
Artificial Sweeteners & Additives β Disrupts gut microbiome & worsens immune responses.
Industrial Seed Oils (Soybean, Canola, Corn Oil) β High in omega-6 fats that promote inflammation.
Dairy & Gluten (for Sensitive Individuals) β Can trigger inflammatory responses in some people.
Example: A person with migraines & fatigue may benefit from reducing sugar and adding turmeric & omega-3s.

How Gut Health Affects Inflammation & Pain
70% of the immune system is located in the gut.
Leaky gut & microbiome imbalances cause inflammation to spread throughout the body.
How to Heal the Gut for Inflammation Control:
Add Prebiotic & Probiotic Foods β Fermented foods, fiber, resistant starch.
Remove Inflammatory Foods β Avoid sugar, gluten, and artificial additives.
Use Bone Broth & Collagen β Repairs gut lining & reduces systemic inflammation.
Take L-Glutamine & Zinc β Helps restore gut barrier integrity.
Example: A person with autoimmune inflammation & digestive issues may benefit from gut healing before focusing on other treatments.
The Role of Blood Sugar in Chronic Inflammation
High blood sugar leads to insulin resistance, which increases inflammation.
Balancing blood sugar improves pain, reduces brain fog, and boosts metabolism.
How to Stabilize Blood Sugar for Less Inflammation:
Eat Protein & Healthy Fats with Every Meal β Slows glucose absorption.
Avoid Processed Carbs & Sugary Drinks β Prevents insulin spikes.
Try Intermittent Fasting (12-16 Hours) β Helps regulate insulin & inflammation.
Exercise Daily β Increases insulin sensitivity & lowers inflammation.
Example: A person with chronic joint pain & fatigue may need blood sugar balancing to lower inflammation.
Managing Stress & Sleep for Long-Term Inflammation Control
Chronic stress increases cortisol, which worsens inflammation.
Poor sleep increases inflammatory markers (CRP, IL-6).
Best Functional Medicine Strategies for Lowering Stress & Inflammation:
Daily Meditation & Deep Breathing β Lowers cortisol & improves nervous system function.
Magnesium Glycinate & L-Theanine β Supports relaxation & reduces stress-driven inflammation.
Prioritize Deep Sleep (7-9 Hours Per Night) β Essential for cellular repair.
Use Adaptogenic Herbs (Ginsenoside, Rhodiola, Holy Basil) β Helps regulate stress response.
Example: People with stress-induced inflammation & pain need nervous system regulation & sleep optimization.
Functional Medicineβs Inflammation Reduction Plan
Step 1: Identify & Remove Inflammatory Triggers β Get lab testing for gut health, insulin resistance, and immune markers.
Step 2: Optimize Anti-Inflammatory Nutrition β Eat omega-3s, polyphenols, and antioxidant-rich foods.
Step 3: Heal the Gut & Improve Detox Pathways β Use probiotics, fiber, and liver support.
Step 4: Reduce Stress & Improve Sleep β Practice breathwork, deep sleep optimization.
Step 5: Use Targeted Nutrients & Supplements β Turmeric, omega-3s, magnesium, vitamin D.
Want a personalized Functional Medicine plan to reduce inflammation & pain?
Schedule a consultation today to start healing naturally!